Oncofertility counseling and fertility preservation in premenopausal women with early breast cancer

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Published: 18 Dec 2025
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Dr Matteo Lambertini - University of Genova, Genova, Italy

Dr Matteo Lambertini presents the findings from the PREFER study, a multicenter prospective cohort study on oncofertility counseling and fertility preservation in premenopausal women with early breast cancer.

The study found that a majority of patients accepted gonadotropin-releasing hormone agonist during chemotherapy, with 25% of patients under 40 opting for cryopreservation.

The study also showed no detrimental effect of controlled ovarian stimulation for oocyte cryopreservation on disease-free survival or overall survival.