Dr Vanita Noronha speaks at the Choosing Wisely Meeting & BMC Conclave about key aspects of genitourinary cancers, focusing on informed treatment decisions. She covers kidney cancer and compares adjuvant therapies such as pembrolizumab and TKIs. She presents treatment options for metastatic RCC, including first-line therapies. She explains the role of lymph node involvement in penile cancer and the impact of adjuvant chemotherapy. Finally, she discusses prostate cancer treatments, highlighting the effectiveness of lower doses of abiraterone and ongoing optimisation studies.